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MYP_017726
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Basic Information
Caerin-1.19 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C127H212N32O29
Standard
Sequence
GLFKVLGSVAKHLLPHVAPIIAEKL
Physicochemical Analysis
2651.24 Da
9.70
1.93
1.62
0.0774
0.90
0.59
0.37
12.20
156.00
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.09
-2.92
31.0
33.0
86.0
188.0
5.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040410 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0042347 VERIFIED: YES
Provenance & Taxonomy
Australian dainty green [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Lactococcus lactis, Streptococcus uberis, Staphylococcus epidermidis
25 μg/mL
MIC
PaperNew caerin antibiotic peptides from the skin secretion of the Dainty Green Tree Frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry
RECORD: Rec_0048294 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
12 μg/mL
MIC
PMID16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16554081/
RECORD: Rec_0087710 VERIFIED: YES
Provenance & Taxonomy
Australian dainty green [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Micrococcus luteus, Staphylococcus aureus ATCC 29213, Listeria innocua
12 μg/mL
MIC
PaperNew caerin antibiotic peptides from the skin secretion of the Dainty Green Tree Frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry
RECORD: Rec_0103453 VERIFIED: YES
Provenance & Taxonomy
Litoria gracilenta [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral
Leuconostoc lactis
3 μg/mL
MIC
PMID26026377;16554081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
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