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MYP_017682
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Basic Information
EcAMP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
37 amino acids
C165H274N70O55S5
Standard
Sequence
GSGRGSCRSQCMRRHEDEPWRVQECVSQCRRRRGGGD
Physicochemical Analysis
4278.70 Da
9.47
3.82
3.50
0.1033
-1.61
0.64
-0.61
137.41
15.68
0.0270
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2100.39
-31.70
82.0
65.0
147.0
295.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169010 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
B. sorokiniana
18.2 μM
IC50
PaperDisulfide-stabilized helical hairpin structure and activity of a novel antifungal peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli).
RECORD: Rec_0177522 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Hairpin-like peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 11-25
Bio-Activity Profile
Antimicrobial Antifungal Anti-protist
Colletotrichum graminicola
10 μM
EC50
PaperPubMed PMID 21561864 | PubMed PMID 24275140 PMID21561864;24275140 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21561864/
RECORD: Rec_0178993 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Hairpin-like peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 11-25
Bio-Activity Profile
Antimicrobial Antifungal Anti-protist
Fusarium oxysporum
8.5 μM
IC50
PaperPubMed PMID 21561864 | PubMed PMID 24275140 PMID21561864;24275140 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21561864/
RECORD: Rec_0185534 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Plant]
Hairpin-like peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 11-25
Bio-Activity Profile
Antimicrobial Antifungal Anti-protist
Aspergillus niger
32 μM
EC50
PaperPubMed PMID 21561864 | PubMed PMID 24275140 PMID21561864;24275140 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21561864/
RECORD: Rec_0190210 VERIFIED: YES
Provenance & Taxonomy
Echinochloa crus-galli [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal
Diplodia maydis
10 μM
EC50
PaperPubMed PMID: 22940285 | PubMed PMID: 21561864 PMID22940285;21561864 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22940285/
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