Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC506H852N138O151S13

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNLYVKRCLNDIGICKKTCKPEEVVKASVMCGKHRACCVPADKRSAYPSFCARPKTTRTSTVTATATTTTTTTLMSLMTTMAASPVSPTT
    

Molecular Weight11701.86 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.13

Charge Density (pH 7.0) 0.0873

GRAVY Index0.21

Hydrophobic Moment 0.55

Boman Index0.07

Instability Index46.65

Aliphatic Index 76.97

Aromaticity 0.0459

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4611.11

LogP -53.68

H-bond Donors 173.0

H-bond Acceptors 175.0

Rotatable Bonds 382.0

Heavy Atoms 808.0

Ring Count 12.0

Amide Bonds 111.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0212891 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence