Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2304H3626N614O654S11

DescriptionStandard

        TNPGFVVRITQSGLDYAHQQGIAILEKQLAQLKLPDISGDSRVMRVGKVHYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFYFVRDHGSFDLKVENVYIKISLMLGSDTAGKPTISTSDCSTRISKVRVLFSGKFGWLYNLFHSAIESRFRKILEGKVCDLVAKSVHNELQTYLQTLPVTSRIDAKTGIDYSLVAPPTATAQSLDADLKGEFYSLAHRSTVPFSPLPLDFPSDHDRMVYFGASSYFFNTAGIAYHKAGALVFEITDATIPKEADFHLNTSIFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPEGISLRPIVDAQAYAILPDSSLAPLFVLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGSFQVRTMQSLMNILTSSVLLPRLNARLDEGFPLPLLDRIQLSNILMRFHQNFLLLGADVQFQPQ
    

Molecular Weight50743.87 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)4.46

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.0098

GRAVY Index0.06

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index37.24

Aliphatic Index 101.34

Aromaticity 0.0965

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239641 VERIFIED: NO

Provenance & Taxonomy

OrganismOrigma solitaria [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria