Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC59H100N16O18S2

DescriptionStandard

        CDVIALLACHLNT
    

Molecular Weight1385.65 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0901

GRAVY Index1.37

Hydrophobic Moment 0.32

Boman Index0.41

Instability Index76.39

Aliphatic Index 157.69

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 541.82

LogP -4.35

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 43.0

Heavy Atoms 95.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272090 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Entry inhibition

TargetWest Nile virus (WNV); Vero cells

Activity65.2±14.5 %

MethodqPCR WNV entry inhibition assay

Half-LifeMammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h

PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 Feb;81(4):2047-55. | DOI:10.1128/JVI.01840-06 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/

RECORD: Rec_0305844 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetWest Nile virus (WNV); Vero cells

Activity65.2±14.5 %

MethodqPCR WNV entry inhibition assay

RECORD: Rec_0374011 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Non-cytotoxic

TargetVero cells

MethodLDH cytotoxicity assay (no significant cytotoxicity up to 500 μM)

RECORD: Rec_0406624 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetWest Nile virus (WNV); Vero cells

Activity96.3±2.7 %

MethodqPCR WNV attachment inhibition assay

RECORD: Rec_0406632 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

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