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MYP_017644
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Basic Information
Microcin J25
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
21 amino acids
C101H141N23O28
Standard
Sequence
GGAGHVPEYFVGIGTPISFYG
Physicochemical Analysis
2125.34 Da
5.24
-1.15
-1.41
-0.0549
0.40
0.34
0.49
28.16
69.52
0.1905
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.64
-6.10
26.0
28.0
60.0
152.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164761 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli AB1133
0.02 μg/mL
MIC
PMID1429464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0229778 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
562
Structure & Mods
side-chain-to-backbone lasso peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella species
PMID1429464;10092860;14531690;14531661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0270849 VERIFIED: YES
Provenance & Taxonomy
E. coli AY25 [Plant]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
residue Gly1 and the beta-carboxy side chain of Glu8
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
PMID34314160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34314160/
RECORD: Rec_0284274 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
S. newport
0.01 μg/mL
MIC
PMID1429464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0288567 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella species
PMID1429464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
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