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MYP_017644
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Basic Information
Microcin J25
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
21 amino acids
C101H141N23O28
Standard
Sequence
GGAGHVPEYFVGIGTPISFYG
Physicochemical Analysis
2125.34 Da
5.24
-1.15
-1.41
-0.0549
0.40
0.34
0.49
28.16
69.52
0.1905
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.64
-6.10
26.0
28.0
60.0
152.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0111354 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
562
Structure & Mods
side-chain-to-backbone lasso peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PMID1429464;10092860;14531690;14531661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0122950 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
562
Structure & Mods
side-chain-to-backbone lasso peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli AB1133
0.02 μg/mL
MIC
PMID1429464;10092860;14531690;14531661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0125724 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
562
Structure & Mods
side-chain-to-backbone lasso peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli BM21
0.08 μg/mL
MIC
PMID1429464;10092860;14531690;14531661 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
RECORD: Rec_0139368 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Bacteriocin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Mannheimia haemolytica
100 μg/mL
MBC
PMID34112244 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34112244/
RECORD: Rec_0153365 VERIFIED: YES
Provenance & Taxonomy
Escherichia coli [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli BM21
0.08 μg/mL
MIC
PMID1429464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1429464/
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