Peptide Database

Peptide NameTigerinin-4 (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC57H94N14O13S2

DescriptionStandard

        RVCYAIPLPIC
    

Molecular Weight1247.57 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0672

GRAVY Index1.35

Hydrophobic Moment 0.37

Boman Index0.37

Instability Index45.51

Aliphatic Index 141.82

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 418.87

LogP -0.86

H-bond Donors 16.0

H-bond Acceptors 16.0

Rotatable Bonds 34.0

Heavy Atoms 86.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424151 VERIFIED: YES

Provenance & Taxonomy

OrganismHoplobatrachus tigerinus [Animal]

FamilyTigerin

Structure & Mods

ConfigLinear peptide with a single intramolecular disulfide-stabilized loop [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

C-TermAmidation

Disulfide3-11

Bio-Activity Profile

Function

Antimicrobial Antifungal

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