Peptide Database

Peptide NameT37-R9

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H202N48O27S

DescriptionStandard

        DIVKVTVYDCIRRRRRRRRR
    

Molecular Weight2673.16 Da

Isoelectric Point (pI)11.91

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.53

Charge Density (pH 7.0) 0.3875

GRAVY Index-1.47

Hydrophobic Moment 0.56

Boman Index-0.98

Instability Index232.51

Aliphatic Index 82.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1314.40

LogP -13.62

H-bond Donors 54.0

H-bond Acceptors 36.0

Rotatable Bonds 94.0

Heavy Atoms 187.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250341 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays