Peptide Database

Peptide Name[C20A, C27A]GeXIVA

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC139H231N55O41S2

DescriptionStandard

        TCRSSGRYCRSPYDRRRRYARRITDAAV
    

Molecular Weight3392.80 Da

Isoelectric Point (pI)11.19

Net Charge (pH 7.0)6.38

Net Charge (pH 7.4) 6.15

Charge Density (pH 7.0) 0.2278

GRAVY Index-1.36

Hydrophobic Moment 0.88

Boman Index-0.68

Instability Index154.26

Aliphatic Index 35.00

Aromaticity 0.1071

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1633.77

LogP -21.85

H-bond Donors 67.0

H-bond Acceptors 50.0

Rotatable Bonds 110.0

Heavy Atoms 237.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039302 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyConotoxin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Analgesic

Targetα9α10 nicotinic acetylcholine receptor