Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2317H3664N596O679S18

DescriptionStandard

        MMLARPYCAVVVLLLLAGVSRTGEGNSNPGFMARITKKGLEYVQQYVVTTLKEQLSTIRLPDLSGHSKIDLIGWVSYDFHSLKIHRFVLQNWNLNLLPELGIGVFLSNSYMSVGGDWKVNKAFITLDGSFELKANGISISLSLNLDKDQSGRPTASVTECSNSIGHISIHLSGSLSWILNLFHEIIENNIKMVLEEKVCDMVTEFTTSYLELYLRTLPVTTMIDEVASLDYRLVGAPQVTSEGLDIPFKGEFFSQSHPSHVPFEAPSMMLPPQHDRMIYLAVSQYMLNTAIWVYHHAGCMKVVIQNEDLARLYPNMEVELEVSLESEPLLTLTPGNVTLSPVIDIRGLALLPSSSDQRTLFQLRVNTNVSIAIGVNSNRIVGSVTIGSELKFEVKQSNLGNINKKLMESIFSYYTIKTIYSSLNAKLQEGFPLPLPRETSLNSVELQIHKNLLFVGAYFD
    

Molecular Weight51310.63 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-8.43

Net Charge (pH 7.4) -9.42

Charge Density (pH 7.0) -0.0183

GRAVY Index0.10

Hydrophobic Moment 0.71

Boman Index0.14

Instability Index39.52

Aliphatic Index 106.93

Aromaticity 0.0848

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348976 VERIFIED: NO

Provenance & Taxonomy

OrganismOctodon degus (Degu) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria