Peptide Database

Peptide NamePentastatin-3

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC89H128N26O29S2

DescriptionStandard

        SAPFIECHGRGTCNYYANS
    

Molecular Weight2090.26 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.47

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0248

GRAVY Index-0.51

Hydrophobic Moment 0.44

Boman Index0.02

Instability Index97.72

Aliphatic Index 31.05

Aromaticity 0.1579

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 893.54

LogP -11.81

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 62.0

Heavy Atoms 146.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0422401 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPentastatin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-angiogenic

TargetEndothelial screening context

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2