Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC154H261N47O44S4

DescriptionStandard

        LRKYYCKIRSGRCALIGCLPKEEEIGRCSLSG
    

Molecular Weight3603.27 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1164

GRAVY Index-0.25

Hydrophobic Moment 0.57

Boman Index-0.15

Instability Index69.07

Aliphatic Index 88.44

Aromaticity 0.0625

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1495.34

LogP -14.57

H-bond Donors 59.0

H-bond Acceptors 52.0

Rotatable Bonds 124.0

Heavy Atoms 249.0

Ring Count 3.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432264 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetBurkholderia cepacia ATCC 25416

Activity>19 μM

MethodMBC (microdilution; ≥99.9% killing)

RECORD: Rec_0432265 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetBurkholderia cepacia ATCC 25416

Activity>19 μM

MethodLD90 (microdilution; 90% killing)

RECORD: Rec_0432266 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetBurkholderia cepacia ATCC 17759

Activity>19 μM

MethodMBC (microdilution; ≥99.9% killing)

RECORD: Rec_0432267 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetBurkholderia cepacia ATCC 17759

Activity>19 μM

MethodLD90 (microdilution; 90% killing)

RECORD: Rec_0432268 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds reported, sites unresolved

Bio-Activity Profile

Function

Antibacterial Antimicrobial

TargetBurkholderia stabilis NCTC 13011

Activity>19 μM

MethodMBC (microdilution; ≥99.9% killing)

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