Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC154H261N47O44S4

DescriptionStandard

        LRKYYCKIRSGRCALIGCLPKEEEIGRCSLSG
    

Molecular Weight3603.27 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1164

GRAVY Index-0.25

Hydrophobic Moment 0.57

Boman Index-0.15

Instability Index69.07

Aliphatic Index 88.44

Aromaticity 0.0625

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1495.34

LogP -14.57

H-bond Donors 59.0

H-bond Acceptors 52.0

Rotatable Bonds 124.0

Heavy Atoms 249.0

Ring Count 3.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062490 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)