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MYP_017538
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C247H393N63O81S4
Standard
Sequence
MEKETTIIESIQEVSLEELDQIIGAGKNGVFKTISHECHLNTWAFLATCCS
Physicochemical Analysis
5669.40 Da
4.63
-5.34
-5.71
-0.1047
0.04
0.49
0.14
30.59
93.73
0.0588
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2322.36
-22.88
82.0
82.0
193.0
395.0
6.0
54.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038642 VERIFIED: NO
Provenance & Taxonomy
Streptococcus suis [Bacterium]
Lantibiotic
Structure & Mods
thioether-cyclized lantibiotic scaffold [Cyclic]
post-translationally modified ribosomal peptide [Modified]
Lanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A822W1M6/entry
RECORD: Rec_0045041 VERIFIED: NO
Provenance & Taxonomy
Streptococcus gallolyticus [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A380KAE6/entry
RECORD: Rec_0061029 VERIFIED: NO
Provenance & Taxonomy
Streptococcus macedonicus [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ6049
RECORD: Rec_0122533 VERIFIED: NO
Provenance & Taxonomy
Streptococcus [Bacterium]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7065
RECORD: Rec_0201023 VERIFIED: NO
Provenance & Taxonomy
Streptococcus macedonicus [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID17581139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17581139/; https://www.uniprot.org/uniprotkb/A6MER0/entry; https://bblserver.org.in/ampdb/
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