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MYP_017521
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Basic Information
CA
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C89H151N21O18
Standard
Sequence
KWKLFKKLKVLTTGL
Physicochemical Analysis
1803.28 Da
10.60
4.76
4.54
0.3170
0.00
0.46
0.01
-28.99
123.33
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
657.07
-0.97
24.0
23.0
64.0
128.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0185891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa OT97
8 μM
MIC
PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0255895 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D21
2 μM
MIC
PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0351225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
P. falciparum
9 μM
IC50
PaperShortened cecropin A-melittin hybrids. Significant size reduction retains potent antibiotic activity.
RECORD: Rec_0384144 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Cowan 1
51 μM
MIC
PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0395936 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis Bs11
1 μM
MIC
PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
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