Peptide Database

Peptide NameTELODIN (DKY21)

Function Ontology

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC105H186N46O33

DescriptionStandard

        YGRKKRRERRRGSRNGTEETK
    

Molecular Weight2620.89 Da

Isoelectric Point (pI)11.63

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.3221

GRAVY Index-2.95

Hydrophobic Moment 0.65

Boman Index-1.13

Instability Index127.33

Aliphatic Index 0.00

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1392.59

LogP -19.61

H-bond Donors 54.0

H-bond Acceptors 40.0

Rotatable Bonds 97.0

Heavy Atoms 184.0

Ring Count 1.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0249703 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPolypeptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Antioxidant Nephroprotective

Target3-6 month old wild mice (In vivo)

MethodWestern blot; Immunofluorescence; qRT-PCR; Histology

RECORD: Rec_0354684 VERIFIED: NO