Peptide Database

Peptide NameQAPRFI-amide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC34H54N10O8

DescriptionStandard

        QAPRFI
    

Molecular Weight730.85 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.1267

GRAVY Index-0.08

Hydrophobic Moment 0.84

Boman Index-0.01

Instability Index27.87

Aliphatic Index 81.67

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 305.02

LogP -1.83

H-bond Donors 10.0

H-bond Acceptors 9.0

Rotatable Bonds 21.0

Heavy Atoms 52.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0004125 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyQAPRFI-amide

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0032160 VERIFIED: NO

Provenance & Taxonomy

OrganismAplysia californica [Animal]

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

-

RECORD: Rec_0186871 VERIFIED: NO

Provenance & Taxonomy

OrganismAplysia californica [Animal]

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0296345 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/