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MYP_017428
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
46 amino acids
C231H368N58O70S4
Standard
Sequence
MTNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
Physicochemical Analysis
5206.00 Da
8.93
2.47
2.19
0.0536
-0.33
0.46
-0.03
17.56
63.48
0.1087
8480.00
8605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2087.42
-21.54
77.0
77.0
169.0
363.0
8.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053625 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes serotype M4 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID16636287 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16636287/; https://www.uniprot.org/uniprotkb/Q1J6S8/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0068276 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes [Bacterium]
Lantibiotic
Structure & Mods
thioether-cyclized lantibiotic scaffold [Cyclic]
post-translationally modified ribosomal peptide [Modified]
Lanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A660A2F9/entry