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MYP_017412
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Basic Information
229E-HCoV-HR1P
Antiviral
Standard
56 amino acids
C251H410N74O88S
Standard
Sequence
AASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQ
Physicochemical Analysis
5904.45 Da
5.30
-1.12
-1.36
-0.0199
-0.14
0.62
0.07
31.06
88.93
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2682.23
-38.41
88.0
89.0
199.0
414.0
3.0
69.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015578 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human hepatocellular carcinoma Huh7
0-10 % Cytotoxicity
Cytotoxicity
PMID30989115;29415501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0041444 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus 229E [Virus]
HR2-derived fusion inhibitor
11137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus 229E
5.7 μM
IC50
PaperPeptide-based membrane fusion inhibitors targeting HCoV-229E spike protein HR1 and HR2 domains PMID29415501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29415501/
RECORD: Rec_0059674 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HCoV-229E PsV
PMID30989115;29415501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
RECORD: Rec_0098103 VERIFIED: YES
Provenance & Taxonomy
Human coronavirus 229E [Virus]
HR2-derived fusion inhibitor
11137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human coronavirus 229E
13.24 μM
IC50
PaperPeptide-based membrane fusion inhibitors targeting HCoV-229E spike protein HR1 and HR2 domains PMID29415501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29415501/
RECORD: Rec_0106540 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HCoV-229E
PMID30989115;29415501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30989115/
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