Peptide Database

Peptide NameTCTP (1-9) deletion mutant

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC51H86N12O14S

DescriptionStandard

        MIIYRDLIS
    

Molecular Weight1123.37 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0555

GRAVY Index1.01

Hydrophobic Moment 0.37

Boman Index0.28

Instability Index-9.90

Aliphatic Index 173.33

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 435.78

LogP -1.11

H-bond Donors 16.0

H-bond Acceptors 15.0

Rotatable Bonds 37.0

Heavy Atoms 78.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0418406 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermRhodamine B

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2