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MYP_017404
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Basic Information
Neutrophil antibiotic peptide NP-3 (RatNP-3a, RatNP-3b; Rodents, mammals, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
29 amino acids
C130H220N48O39S6
Standard
Sequence
CSCRTSSCRFGERLSGACRLNGRIYRLCC
Physicochemical Analysis
3271.83 Da
9.25
4.70
4.41
0.1622
-0.17
0.72
-0.26
37.39
57.24
0.0690
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1451.29
-20.49
62.0
50.0
109.0
223.0
2.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108803 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
1-29; 3-18; 8-28
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Staphylococcus aureus 502A
PaperPubMed PMID: 2254017 | PubMed PMID: 7594610 PMID2254017;7594610 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
RECORD: Rec_0121898 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Escherichia coli ML-35, Staphylococcus aureus 502A, Cryptococcus neoformans A-383
PaperPurification and antimicrobial properties of three defensins from rat neutrophils
RECORD: Rec_0240701 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 502A
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0260427 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0307142 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 20.7%, T 27.6%, C 51.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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