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MYP_017404
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Basic Information
Neutrophil antibiotic peptide NP-3 (RatNP-3a, RatNP-3b; Rodents, mammals, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
29 amino acids
C130H220N48O39S6
Standard
Sequence
CSCRTSSCRFGERLSGACRLNGRIYRLCC
Physicochemical Analysis
3271.83 Da
9.25
4.70
4.41
0.1622
-0.17
0.72
-0.26
37.39
57.24
0.0690
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1451.29
-20.49
62.0
50.0
109.0
223.0
2.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030251 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
1-29; 3-18; 8-28
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Escherichia coli ML-35
PaperPubMed PMID: 2254017 | PubMed PMID: 7594610 PMID2254017;7594610 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
RECORD: Rec_0045130 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
Cyclization
1-29; 3-18; 8-28
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Candida albicans 820
PaperPubMed PMID: 2254017 | PubMed PMID: 7594610 PMID2254017;7594610 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2254017/
RECORD: Rec_0049482 VERIFIED: YES
Provenance & Taxonomy
Mammalia [Animal]
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0062108 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperEisenhauer P. B., Harwig S. S., Szklarek D., Ganz T., Selsted M. E., Lehrer R. I.. Purification and antimicrobial properties of three defensins from rat neutrophils. Infect. Immun., 57, 2021-2027, 1989.
RECORD: Rec_0087445 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
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