Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length441 amino acids

Chemical FormulaC2192H3481N561O627S16

DescriptionStandard

        MFLWCVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALALVPDTGVILSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVTSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIADINPHLKTLNVLAKVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTNMLYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGGFIPQIEKMYPGLMMKLLVETVKEPLMTFEPNNMTVQASSTVTAYAIQPNSTLSPLFFWSHNCSLYIYTKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLQVLKVR
    

Molecular Weight48238.51 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)9.91

Net Charge (pH 7.4) 9.28

Charge Density (pH 7.0) 0.0225

GRAVY Index0.17

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index30.73

Aliphatic Index 102.29

Aromaticity 0.0907

Extinction Coeff. Reduced 47330.00

Extinction Coeff. Oxidized 47580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095203 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria