Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC766H1234N208O225S7

DescriptionStandard

        MQLSRKGLEAIKFFEGLKLEAYKDSAGIPTIGYGTIRIDGKPVKMGMKITAEQAEQYLLADVEKFVAAVNKAIKVPTSQNEFDALVSETYNIGITAMQDSTFIKRHNAGNKVGCAEAMQWWNKITVKGKKVTSNGLKNRRRMEADIYLDSVYPK
    

Molecular Weight17181.71 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)6.59

Net Charge (pH 7.4) 6.25

Charge Density (pH 7.0) 0.0428

GRAVY Index-0.37

Hydrophobic Moment 0.69

Boman Index-0.02

Instability Index30.57

Aliphatic Index 81.75

Aromaticity 0.0844

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7062.90

LogP -66.39

H-bond Donors 244.0

H-bond Acceptors 240.0

Rotatable Bonds 592.0

Heavy Atoms 1206.0

Ring Count 20.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247831 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage EC6 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic