Peptide Database

Peptide NameBig LEN

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Membrane / Ion-channel modulation ▸ Ion channel modulation

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC80H135N23O21

DescriptionStandard

        LETPAPQVPARRLLPP
    

Molecular Weight1755.07 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0477

GRAVY Index-0.34

Hydrophobic Moment 0.37

Boman Index-0.04

Instability Index124.72

Aliphatic Index 103.75

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 680.29

LogP -4.93

H-bond Donors 21.0

H-bond Acceptors 22.0

Rotatable Bonds 48.0

Heavy Atoms 124.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209294 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyProSAAS

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide precursor Secretory peptide

RECORD: Rec_0333734 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBig LEN

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods3:O-linked (GalNAc...) threonine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min