Peptide Database

Peptide NameBrevinin-2SN3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC133H233N37O36S2

DescriptionStandard

        GAFGNLLKGVAKKAGLKILSIAQCKLSGTC
    

Molecular Weight2990.63 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.50

Charge Density (pH 7.0) 0.1578

GRAVY Index0.55

Hydrophobic Moment 0.61

Boman Index0.21

Instability Index-9.07

Aliphatic Index 114.00

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1184.19

LogP -12.07

H-bond Donors 43.0

H-bond Acceptors 43.0

Rotatable Bonds 106.0

Heavy Atoms 208.0

Ring Count 1.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401661 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide24-30

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans ATCC 10231

Activity>400 μM

MethodMIC

RECORD: Rec_0401679 VERIFIED: YES