Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC314H490N80O101S6

DescriptionStandard

        MTKDMIVKAWKDPFARPSNAPSNPAGDVYMELEEAELDQVVGGTEAQAFATIGAKCTVETCSAVIWC
    

Molecular Weight7194.12 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-5.51

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0823

GRAVY Index-0.04

Hydrophobic Moment 0.60

Boman Index0.12

Instability Index39.50

Aliphatic Index 70.00

Aromaticity 0.0746

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2873.75

LogP -28.73

H-bond Donors 99.0

H-bond Acceptors 102.0

Rotatable Bonds 231.0

Heavy Atoms 501.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111914 VERIFIED: NO

Provenance & Taxonomy

OrganismKroppenstedtia pulmonis [Animal]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria