Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer ▸ Tumor T-cell antigen

Immunology ▸ Epitope/vaccine antigen ▸ T-cell epitope

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC48H74N12O13S

DescriptionStandard

        NSQPVWLCL
    

Molecular Weight1059.24 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0278

GRAVY Index0.44

Hydrophobic Moment 0.14

Boman Index0.29

Instability Index108.20

Aliphatic Index 118.89

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 409.53

LogP -2.68

H-bond Donors 14.0

H-bond Acceptors 14.0

Rotatable Bonds 30.0

Heavy Atoms 74.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0273342 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Immunomodulatory Tumor T-cell antigen T-cell epitope

RECORD: Rec_0432229 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTumor-associated antigen peptide

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Tumor T-cell antigen T-cell epitope Immunomodulatory Anticancer

TargetHLA-A*2402 target cells pulsed with RNF43-721

Activity68 %

MethodCTL cytotoxicity assay (E:T 20:1)