Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC231H389N67O75S7

DescriptionStandard

        DFNLDLLSVSKKDSGASPRITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK
    

Molecular Weight5529.42 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0544

GRAVY Index0.05

Hydrophobic Moment 0.31

Boman Index0.05

Instability Index28.72

Aliphatic Index 75.47

Aromaticity 0.0189

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2269.37

LogP -30.86

H-bond Donors 85.0

H-bond Acceptors 87.0

Rotatable Bonds 185.0

Heavy Atoms 380.0

Ring Count 5.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040246 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0256581 VERIFIED: NO