Peptide Database

Peptide NameSLAY-screened peptide P4340

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC99H158N30O27S2

DescriptionStandard

        CNHFSAKLMRNTHGPPDIIL
    

Molecular Weight2264.63 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)0.92

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0462

GRAVY Index-0.24

Hydrophobic Moment 0.47

Boman Index0.04

Instability Index8.53

Aliphatic Index 83.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 907.86

LogP -8.69

H-bond Donors 31.0

H-bond Acceptors 32.0

Rotatable Bonds 71.0

Heavy Atoms 158.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129562 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/