Peptide Database

Peptide NameCicerarin (Plant defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Antiviral

Antiviral ▸ Anti-HIV

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC96H160N26O31

DescriptionStandard

        VKSTGRADDDLAVKTKYLPP
    

Molecular Weight2174.45 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0367

GRAVY Index-0.71

Hydrophobic Moment 0.55

Boman Index-0.18

Instability Index17.39

Aliphatic Index 78.00

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 931.42

LogP -9.53

H-bond Donors 32.0

H-bond Acceptors 32.0

Rotatable Bonds 70.0

Heavy Atoms 153.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325327 VERIFIED: YES

Provenance & Taxonomy

OrganismCicer arietinum [Plant]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Antiviral

TargetPseudocercospora piricola

Activity8.2 μM

MethodIC50

RECORD: Rec_0416834 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antifungal

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