Peptide Database

Peptide NameTachykinin OctTK-I

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Tachykinin peptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC58H93N13O18S

DescriptionStandard

        KPPSSSEFIGLM
    

Molecular Weight1292.50 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0198

GRAVY Index-0.03

Hydrophobic Moment 0.18

Boman Index0.18

Instability Index83.13

Aliphatic Index 65.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 489.85

LogP -4.57

H-bond Donors 16.0

H-bond Acceptors 19.0

Rotatable Bonds 40.0

Heavy Atoms 90.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022496 VERIFIED: NO

Provenance & Taxonomy

OrganismOctopus vulgaris [Animal]

FamilyTachykinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0104467 VERIFIED: YES

Provenance & Taxonomy

OrganismOctopus vulgaris [Animal]

FamilyTachykinin

Tax ID6645

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator

RECORD: Rec_0225896 VERIFIED: YES

Provenance & Taxonomy

OrganismOctopus vulgaris [Animal]

FamilyTachykinin

Tax ID6645

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Vasoactive Vasodilator

Half-LifeMammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0369753 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/