Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC584H935N175O166S9

DescriptionStandard

        MEQCVHVHRKLPLATINSFSKSVSLFLFLGSDLDAGRICGYGTARCRRNCKRHELRVGKCPNTYPCCLKKWKVNSLNPQKDTKPRGAWLLEMATSQTSEPPFSGPSRWTVPSGSSRLVE
    

Molecular Weight13352.33 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)10.70

Net Charge (pH 7.4) 10.20

Charge Density (pH 7.0) 0.0900

GRAVY Index-0.49

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index41.54

Aliphatic Index 67.14

Aromaticity 0.0756

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5492.78

LogP -61.22

H-bond Donors 201.0

H-bond Acceptors 189.0

Rotatable Bonds 436.0

Heavy Atoms 934.0

Ring Count 24.0

Amide Bonds 126.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192362 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence