Peptide Database

Peptide NameNeuropeptide NPF-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC54H92N20O12

DescriptionStandard

        ARGPQLRLRF
    

Molecular Weight1213.43 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.80

Net Charge (pH 7.4) 2.61

Charge Density (pH 7.0) 0.2796

GRAVY Index-0.68

Hydrophobic Moment 0.33

Boman Index-0.39

Instability Index58.29

Aliphatic Index 88.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 545.22

LogP -4.69

H-bond Donors 20.0

H-bond Acceptors 15.0

Rotatable Bonds 39.0

Heavy Atoms 86.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432208 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptinotarsa decemlineata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Receptor agonist

TargetDmGPCR1

Activity100-200 nM

MethodEC50 (FLIPR calcium assay)

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