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MYP_017192
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Basic Information
D16W (GGN4 analogue peptide with single substitution)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C172H292N46O47S2
Standard
Sequence
GILDTLKQFAKGVGKWLVKGAAQGVLSTVSCKLAKTC
Physicochemical Analysis
3820.57 Da
9.79
4.74
4.49
0.1280
0.40
0.72
0.17
8.24
105.41
0.0541
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1507.46
-14.28
55.0
54.0
132.0
267.0
3.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153629 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
50 μg/mL
MIC
PaperPubMed PMID: 12199716 PMID12199716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12199716/
RECORD: Rec_0156517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Eshchericia coli
10 μg/mL
MIC
PaperPubMed PMID: 12199716 PMID12199716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12199716/
RECORD: Rec_0206260 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
25 μg/mL
MIC
PMID12199716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12199716/
RECORD: Rec_0213179 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas putida
100 μg/mL
MIC
PaperPubMed PMID: 12199716 PMID12199716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12199716/
RECORD: Rec_0245910 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
31-37
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 12199716 PMID12199716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12199716/
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