Peptide Database

Peptide NameDes-Arg-

Function Ontology

Antimicrobial

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC44H60N8O10

DescriptionStandard

        VPPGFTPF
    

Molecular Weight860.99 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0333

GRAVY Index0.49

Hydrophobic Moment 0.40

Boman Index0.53

Instability Index80.97

Aliphatic Index 36.25

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 260.88

LogP -0.54

H-bond Donors 7.0

H-bond Acceptors 10.0

Rotatable Bonds 18.0

Heavy Atoms 62.0

Ring Count 5.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089429 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyDes-Arg

Tax ID317381

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Vasoactive Vasodilator Receptor modulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0133617 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]; Physalaemus nattereri [Animal]

FamilyBradykinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0151871 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyDes-Arg

Tax ID317381

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Vasoactive Vasodilator Receptor modulation

Targetvitro relaxation of rat arterial smooth muscle

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0416998 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0425403 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

FamilyDes

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

-