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MYP_017156
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Basic Information
Picturin 2BN
Anticancer
Antimicrobial
Standard
23 amino acids
C108H195N27O28S2
Standard
Sequence
GLMDMLKKVGKVALTVAKSALLP
Physicochemical Analysis
2384.00 Da
10.00
2.76
2.55
0.1199
0.77
0.69
0.24
-0.52
135.65
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
876.57
-5.04
30.0
33.0
83.0
165.0
1.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071276 VERIFIED: YES
Provenance & Taxonomy
Boana boans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
breast adenocarcinoma MDA-MB-231 cells
26.3 μM
LC50
PaperPurification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae).
RECORD: Rec_0093043 VERIFIED: YES
Provenance & Taxonomy
Boana boans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
This peptide is not selective due to similar LC50 to non-cancer cell human umbilical vein endothelial cells HUVEC
53.3 μM
LC50
PaperPurification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae).
RECORD: Rec_0152314 VERIFIED: YES
Provenance & Taxonomy
Boana boans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 35218
7.8 μM
MIC
PaperPurification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae).
RECORD: Rec_0152389 VERIFIED: YES
Provenance & Taxonomy
Boana boans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Pseudomonas aeruginosa ATCC 9072
15.6 μM
MIC
PaperPurification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae).
RECORD: Rec_0184505 VERIFIED: YES
Provenance & Taxonomy
Boana boans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Also showed cytotoxicity to cancer cells: lung adenocarcinoma A549
23 μM
LC50
PaperPurification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae).
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