Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length440 amino acids

Chemical FormulaC2168H3478N556O615S21

DescriptionStandard

        MSPCCLLALLALIPLTLAANPGVKVKLTDKGIEYGKQIGMASLQQKLKTIKVPDLSGTEKVPHVGKVKYSLTGMTIVNLGLPKSALVLVPGTGVSLAITNAFINLHGNWRVRYFRFMQDRGSFDLAVNGLTITANIAIKSDETGRPMVSTVNCVANVGRASIKFHGGASWLYNLFKSYIDKALRSALQKQICPLVADAITDMNQHLKTFNVLAKVDQYAEIEYSMGTSPTISKSSMEFSLKGEFYNIVKHQEPPFSPTPFSLPPQGNNMLYIGVSSFTPNSAGFVYNNAGALSLYVTDDMIPPSSPIRLNTGTFGVFIPEIAKRFPGMMMKLLVKTVKEPTISLEPNNVTVQASGTVTAYAIQPNTTLSPLFVLNMVSQSVQSLDNIFLMVLKVVVIPKVNARLEKGFPLPSIGKMNLVNTQLQVLKDYMLIGTDVQFTG
    

Molecular Weight47845.53 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)13.90

Net Charge (pH 7.4) 13.28

Charge Density (pH 7.0) 0.0316

GRAVY Index0.17

Hydrophobic Moment 0.70

Boman Index0.16

Instability Index32.45

Aliphatic Index 100.09

Aromaticity 0.0795

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412434 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria