Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length199 amino acids

Chemical FormulaC991H1553N277O296S11

DescriptionStandard

        METQMASLSLGRCSLWLLLLGLLLPSASAQALSYREAVLRAVGQLNEKSSEVNLYRLLELDPPPKDAEDQGARKPVSFRVKETVCPRTSQQPVEQCDFRENGLVKQCVGTVTRYWIRGDFDITCNDLCWDGLVTLGSPLSPKGPWLAYLSVVWRFNHRLQTSYGRFRVWGYSAGCGTHSEESYQDQVLNSESPLECMRV
    

Molecular Weight22436.33 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-1.37

Net Charge (pH 7.4) -1.85

Charge Density (pH 7.0) -0.0069

GRAVY Index-0.28

Hydrophobic Moment 0.65

Boman Index-0.02

Instability Index37.28

Aliphatic Index 85.18

Aromaticity 0.0905

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9226.33

LogP -115.29

H-bond Donors 330.0

H-bond Acceptors 308.0

Rotatable Bonds 717.0

Heavy Atoms 1575.0

Ring Count 37.0

Amide Bonds 215.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0149481 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCathelicidin

Tax ID9925

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal