Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC475H762N142O116S8

DescriptionStandard

        MKYLLLNLLVFFILFQLFPVYRCRKSCWVIRGHCRKHCRSGERVKKPCSNGDYCCIAKKINTVPQAPKNAFSRNFRVHSRTAPVAVLKNST
    

Molecular Weight10574.53 Da

Isoelectric Point (pI)10.32

Net Charge (pH 7.0)15.68

Net Charge (pH 7.4) 15.19

Charge Density (pH 7.0) 0.1724

GRAVY Index-0.15

Hydrophobic Moment 0.79

Boman Index-0.08

Instability Index29.97

Aliphatic Index 82.42

Aromaticity 0.1099

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4193.56

LogP -37.71

H-bond Donors 156.0

H-bond Acceptors 143.0

Rotatable Bonds 348.0

Heavy Atoms 741.0

Ring Count 19.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211941 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence