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MYP_017083
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Basic Information
AaeAP2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C94H153N23O24
Standard
Sequence
FLFSLIPSAIAGLVSAIRN
Physicochemical Analysis
1989.36 Da
9.75
0.76
0.56
0.0400
1.46
0.49
0.49
24.59
154.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
744.01
-5.14
26.0
25.0
62.0
141.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0270696 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Hemolytic
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0275260 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
512 μg/mL
MIC
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0283453 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Androctonus aeneas [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
16 μg/mL
MIC
PaperAaeAP1 and AaeAP2: Novel Antimicrobial Peptides from the Venom of the Scorpion, Androctonus aeneas: Structural Characterisation, Molecular Cloning of Biosynthetic Precursor-Encoding cDNAs and Engineering of Analogues with Enhanced Antimicrobial and Anticancer Activities
RECORD: Rec_0287412 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Hemolytic
horse red blood cells
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0291968 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Gram-positive bacteria: Staphylococcus aureus
16 μg/mL
MIC
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
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