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MYP_017083
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Basic Information
AaeAP2
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C94H153N23O24
Standard
Sequence
FLFSLIPSAIAGLVSAIRN
Physicochemical Analysis
1989.36 Da
9.75
0.76
0.56
0.0400
1.46
0.49
0.49
24.59
154.21
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
744.01
-5.14
26.0
25.0
62.0
141.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150867 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0178826 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
32 μg/mL
MIC
RECORD: Rec_0203132 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
16 μg/mL
MIC
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0213429 VERIFIED: YES
Provenance & Taxonomy
Androctonus aeneas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse RBCs
64 μg/mL
Hemolysis
PMID25626077 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25626077/
RECORD: Rec_0245165 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Androctonus aeneas [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans
32 μg/mL
MIC
PaperAaeAP1 and AaeAP2: Novel Antimicrobial Peptides from the Venom of the Scorpion, Androctonus aeneas: Structural Characterisation, Molecular Cloning of Biosynthetic Precursor-Encoding cDNAs and Engineering of Analogues with Enhanced Antimicrobial and Anticancer Activities
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