Peptide Database

Peptide NameColicin-E1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length522 amino acids

Chemical FormulaC2504H4101N731O790S6

DescriptionStandard

        METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTGDWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTINEVLGI
    

Molecular Weight57279.16 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)14.19

Net Charge (pH 7.4) 13.40

Charge Density (pH 7.0) 0.0272

GRAVY Index-0.59

Hydrophobic Moment 0.78

Boman Index-0.13

Instability Index29.08

Aliphatic Index 83.01

Aromaticity 0.0536

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083645 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyChannel forming colicin

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli