Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC923H1400N208O287S7

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFQPFIDLDLKGAVFPVGNYTDSPFVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTLAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPLISLQQDSFTVEIQGSVEVVASLPDSTTQSLFTLNIAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20226.66 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.24

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0828

GRAVY Index0.31

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index48.94

Aliphatic Index 94.89

Aromaticity 0.1304

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7855.58

LogP -87.29

H-bond Donors 266.0

H-bond Acceptors 279.0

Rotatable Bonds 646.0

Heavy Atoms 1425.0

Ring Count 34.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114730 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecile atricapillus (Black-capped chickadee) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria