Peptide Database

Peptide NameT-155

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC172H293N47O57S2

DescriptionStandard

        ENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQST
    

Molecular Weight3995.58 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)0.83

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0237

GRAVY Index-0.76

Hydrophobic Moment 0.58

Boman Index-0.19

Instability Index34.28

Aliphatic Index 89.14

Aromaticity 0.0286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1755.03

LogP -18.35

H-bond Donors 59.0

H-bond Acceptors 60.0

Rotatable Bonds 145.0

Heavy Atoms 278.0

Ring Count 1.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0197483 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman orthopneumovirus [Virus]

FamilyVirus-derived peptide

Tax ID11250;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetRespiratory syncytial virus (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0337426 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 71.4%, E 0.0%, T 0.0%, C 28.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial