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MYP_016985
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Basic Information
Unnamed
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
36 amino acids
C198H303N57O58
Standard
Sequence
YPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRY
Physicochemical Analysis
4409.87 Da
8.34
0.85
0.58
0.0237
-1.21
0.67
-0.30
79.93
70.56
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1888.47
-16.19
66.0
60.0
138.0
313.0
10.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0283057 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Neuropeptide Y / neuropeptide F
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0296326 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
NPY family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
13-Ser: Phosphoserine
Bio-Activity Profile
Hormone NPY-family Neuropeptide signaling
PaperPDB 2DEZ structural record; NMR; chain A; residues 1-36
RECORD: Rec_0386892 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Peptide YY
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
13:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Feeding regulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PMID16819834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16819834/
RECORD: Rec_0418116 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
NPY
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Ser13 Phosphoserine
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
PMID3202875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3202875/