Peptide Database

Peptide Name[125I]Tyr0-CRF (human, rat, mouse)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC217H352N60O66S2

DescriptionStandard

        YSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
    

Molecular Weight4921.61 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-3.05

Net Charge (pH 7.4) -3.37

Charge Density (pH 7.0) -0.0726

GRAVY Index-0.28

Hydrophobic Moment 0.77

Boman Index-0.03

Instability Index51.46

Aliphatic Index 109.29

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2042.53

LogP -16.28

H-bond Donors 69.0

H-bond Acceptors 67.0

Rotatable Bonds 167.0

Heavy Atoms 345.0

Ring Count 6.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195921 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetCRF1 receptor (Human)