Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC340H518N92O83S10

DescriptionStandard

        MLSFLFCFAFFFILAQFLSGEFAVCEPCWLGRGKCRRICTEDEKVVGNCKMNFFCCRRRISTKH
    

Molecular Weight7542.97 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)4.52

Net Charge (pH 7.4) 4.12

Charge Density (pH 7.0) 0.0706

GRAVY Index0.32

Hydrophobic Moment 0.60

Boman Index0.07

Instability Index51.58

Aliphatic Index 67.03

Aromaticity 0.1719

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2824.70

LogP -20.79

H-bond Donors 109.0

H-bond Acceptors 99.0

Rotatable Bonds 249.0

Heavy Atoms 525.0

Ring Count 14.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0344387 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0377912 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence