Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

—

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC190H318N60O48S6

DescriptionStandard

        IRNPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCRKP
    

Molecular Weight4403.32 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)7.78

Net Charge (pH 7.4) 7.43

Charge Density (pH 7.0) 0.1946

GRAVY Index-0.21

Hydrophobic Moment 0.55

Boman Index-0.09

Instability Index47.58

Aliphatic Index 65.75

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1721.96

LogP -18.50

H-bond Donors 66.0

H-bond Acceptors 63.0

Rotatable Bonds 139.0

Heavy Atoms 304.0

Ring Count 8.0

Amide Bonds 41.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0379191 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)